Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
VCAM1 P19320 vascular cell adhesion molecule 1 0.80 0.422 0.808
UGT1A1 P22309 UDP glucuronosyltransferase family 1 member A1 3.3E-06 0.464 0.769
SLCO1B1 Q9Y6L6 solute carrier organic anion transporter family member 1B1 Transporter 1.1E-21 0.538 0.731
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SCARB1 Q8WTV0 scavenger receptor class B member 1 Receptor 6.6E-02 0.559 0.731
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
PLA2G15 Q8NCC3 phospholipase A2 group XV Enzyme 0.38 0.520 0.769
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PCSK9 Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 2.7E-17 0.482 0.808
NR1H3 Q13133 nuclear receptor subfamily 1 group H member 3 Nuclear receptor 0.90 0.566 0.692
NPC1 O15118 NPC intracellular cholesterol transporter 1 Transporter 6.5E-06 0.518 0.692
NOX1 Q9Y5S8 NADPH oxidase 1 8.7E-08 0.536 0.808
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
MEF2A Q02078 myocyte enhancer factor 2A Transcription factor 0.99 0.585 0.692
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808
LPAL2 Q16609 lipoprotein(a) like 2, pseudogene Enzyme 0.626 0.731
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654